CRISPR DNA damage
 
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CRISPR DNA damage

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(@shamangineer)
Posts: 1023
Noble Member
Topic starter
 

The Sanger scientists didn’t set out to find collateral DNA damage from CRISPR. As they investigated how CRISPR might change gene expression, a “weird thing” showed up, Bradley said: The target DNA was accurately changed, but that set off a chain reaction that engulfed genes far from the target. The scientists therefore changed course.

When they aimed CRISPR at different targets in mouse embryonic stem cells, mouse blood-making cells, and human retinal cells, “extensive on-target genomic damage [was] a common outcome,” they wrote in their paper. In one case, genomes in about two-thirds of the CRISPR’d cells showed the expected small-scale inadvertent havoc, but 21 percent had DNA deletions of more than 250 bases and up to 6,000 bases long.

https://www.statnews.com/2018/07/16/crispr-potential-dna-damage-underestimated/

 
Posted : July 17, 2018 4:01 AM
(@hugh-johnson)
Posts: 57
Trusted Member
 

DNA barely does anything.

"I intend to show you how neo-Darwinism has been invalidated within science itself, as an explanation of how life on earth has evolved and is evolving. It is nevertheless still perpetrated by the academic establishment, if only because it serves so well to promote genetic engineering, a technology that has the potential to destroy all life on earth. Furthermore, neo-Darwinism reinforces a worldview that undermines all moral values and prevents us from the necessary shift to holistic, ecological sciences that can truly regenerate the earth and revitalize the human spirit." Mae-Wan Ho http://www.i-sis.org.uk/paris.php

http://raypeat.com/articles/articles/adaptive-substance.shtml

DNA is just blueprints for proteins and the cell can survive for a long time without DNA. Most of the information about the organism is elsewhere.

 
Posted : September 28, 2018 6:07 PM
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